從2002到2003年，將近10個月的時間，PETA的調查員隱藏身分在Sinclair Research Center，受僱於Iams（愛慕思）的實驗室裡工作。PETA調查員發現在Iams寵物食品清新、健康的包裝下，隱藏的是黑暗且骯髒的秘密。在實驗室，被關在鐵籠裡成天對著水泥牆的狗狗瘋掉了、大腿肌肉被砍掉的狗狗成堆地被丟在骯髒、油漆斑駁的地上、狗狗被割掉了聲帶、生了重病的貓狗在毫無獸醫關照的情況下被扔在籠子裡繼續受苦。
美國農業部審核了PETA提出的抗議後表示該實驗室確實沒有提供獸醫照護、沒有提供受苦的動物麻醉或止痛、沒有提供足夠的空間、沒有做好員工教育訓練，該實驗室同時違反了其他40項聯邦動物福利法規範。Siniclair Research Center付出美金$33,000元（相當於一百零五萬六千元台幣）的罰款。
1. Iams順從壓力，切斷與Siniclair Research Center的關係
根 據Iams表示，實驗中大約70%的動物在家中與飼主同住。在這些實驗中，飼主自願讓寵物在家中居住，參與食品營養成份的實驗。透過訓練，飼主可以輕易 地餵食寵物，並採集寵物的糞便以供實驗室作為參考指標。「居家實驗」已經過奧克拉荷馬州立大學PetSci program證實是有效的。
即使如此，Iams仍舊在他們位於俄亥俄州的實驗室中保留700隻左右的貓狗， 進行非侵入性的營養成分測試。他們宣稱該實驗室提供動物像樣的環境，但他們拒絕讓PETA的代表進入參觀。Iams宣稱有些實驗太過複雜，無法以居家 實驗方式進行。PETA呼籲Iams與獸醫團隊合作來進行這些實驗，因為獸醫具備豐富的醫療經驗，知道哪些食品可以減輕寵物的病痛。
Iams 沒有停止以其他（非狗貓）的動物進行侵入性的實驗。Iams贊助Purdue大學將近$200,000美金來進行一項長達兩年的實驗。實驗過程中，老鼠 的尾巴被黏在籠子頂端，而老鼠的後腿部懸掛在空中。這項實驗的目的是為了造成肌肉萎縮。當PETA提出抗議後，該實驗提前終止。
抵制名單：普瑞納（Purina）、寶路（Pedigree）、皇家（Royal Canin）、愛寶（Alpo）、希爾斯（Hills Science Diet）、
Alpo, Bonio, Felix, Go Cat, Gourmet,
Omega Complete, Proplan, Spillers, Vital Balance, Winalot.
Pedigree, Masterfoods (Mars Inc):
Bounce, Cesar, Chappie, Frolic, James Wellbeloved, Katkins,
Kitekat, Pal, Pedigree Chum, Royal Canin, Sheba,
Techni-cal (US & Canada), Whiskas.
Pedigree also manufacture Thomas rabbit food and Trill bird food.
For nearly 10 months in 2002 and early 2003, a PETA investigator worked undercover at Sinclair Research Center, a laboratory hired by Iams, and discovered a dark and sordid secret beneath the wholesome image of the dog- and cat-food manufacturer. Dogs had gone crazy because they were confined to barren steel cages and cement cells, dogs were left piled on a filthy paint-chipped floor after chunks of muscle had been hacked from their thighs, dogs were surgically debarked, and horribly sick dogs and cats were neglected and left in cages to suffer without any veterinary care. Footage shows that Iams representatives toured the facility and witnessed dogs who were circling in their cells and sweltering in the summer heat. Iams knew the truth yet did nothing to protect the animals.
The U.S. Department of Agriculture investigated PETA's complaint and agreed that the laboratory had failed to provide veterinary care and pain relief to suffering animals, failed to provide animals with adequate space, and failed to train employees—along with nearly 40 other violations of the federal Animal Welfare Act. Sinclair Research Center paid a penalty of $33,000 for its violations.
After intense pressure from PETA and its supporters, Iams agreed to make the following significant changes in its testing program:
• Iams bowed to pressure and severed its ties with Sinclair Research Center.
• Iams ended all invasive and terminal experiments on dogs and cats.
• Iams agreed to begin conducting humane in-home tests for palatability studies.
According to Iams, about 70 percent of the animals now in its tests reside at home with their families. In these studies, people volunteer their companion animals to participate in food and nutrition experiments from the comfort of their own homes. The human guardians can easily be trained to feed the animals and properly collect fecal and urine samples for laboratory analysis to determine the quality of the animal's food. "In-home" studies have been shown to work and have strong scientific support, as shown by the successful PetSci program, which was developed by Dr. Charles Abramson and Dr. Timothy Bowser of Oklahoma State University.
Even so, Iams still keeps up to 700 dogs and cats in its Dayton, Ohio, laboratory for non-invasive nutritional studies. They claim that this laboratory provides a decent environment for the animals, but they refuse to allow a PETA representative to see inside. Iams claims that some studies are too complex for in-home programs, but PETA urges Iams to collaborate with veterinary clinics for studies such as these. Veterinary clinics regularly see patients who suffer from ailments that a particular dog or cat food might help alleviate.
Iams has also refused to end invasive experiments on species other than dogs and cats. For one study, Iams gave Purdue University nearly $200,000 to conduct a two-year study in which experimenters taped the tails of mice to the tops of cages to keep their hind legs suspended in the air. This was done to cause muscular atrophy—the wasting away of muscle tissue. When PETA protested, the experiment was cut short. I
Iams has also fought the release of information from a public university that had conducted a study funded by the company in which a painful disease was induced in dogs. What was Iams hiding?
Iams has made progress, but as an industry leader, it must send an even clearer message: No animal deserves the fate of those who remain in their laboratories. Safe, healthy cat and dog food does not require harming cats and dogs.
PETA continues to press Iams to ban conducting and funding invasive or terminal experiments on all species and to adopt 100 percent humane, non-invasive, and cage-free "in-home" testing, as many of Iams' compassionate competitors have done.
Until Iams agrees, we urge consumers to purchase dog and cat food from companies that do not test on animals. In the meantime, read about some other ways you can help the millions of animals every year who are abused and inadequately cared for, all in the name of research.